Abstract: N-butanol alcohol extract (BF) and ethyl acetate extract (EF) were extracted by using n-butanol and ethyl acetate from alcohol extract of corn silk respectively in this paper.The main functional components and their effects on alloxan-induced diabetic mice were analyzed.The results showed that both of BF and EF could obviously improve the symptoms of "weight loss and blood sugar increase",reduce the fasting blood glucose concentration significantly (P<0.05) and improve the glucose tolerance of diabetic mice significantly (P<0.01).Furthermore,the effect of n-butanol extract was better than that of ethyl acetate extract.The contents of total saponins,total flavonoids and total polyphenols in n-butanol extract were higher than those of ethyl acetate extract.The same trend was observed in the contents of the flavones glycoside A and B,and the latter had higher contents in the two extractions.It was concluded that the n-butanol extract from corn silk had a better antidiabetic effect,and its main hypoglycemic components were saponins,flavonoids and polyphenols.In addition,monomer compound B is the main component in flavonoids.