Abstract: Hyperlipidemia and hyperglycemia are common chronic metabolic diseases with complex pathogenesis.Intestinal flora plays an important role on the early onset and deterioration stage of metabolic diseases.Probiotics are effective means on regulating the balance of intestinal flora.They are used for the prevention and alleviation of hyperlipidemia and hyperglycemia through improving the intestinal permeability,enhancing immunity and other mechanisms.In this review,we summarized the research advances on the classification of probiotics and their mechanisms on alleviation of hyperlipidemia and hyperglycemia,in order to provide references for related research and application of probiotics.